{"id":129587,"date":"2020-09-26T11:41:38","date_gmt":"2020-09-26T08:41:38","guid":{"rendered":"http:\/\/epochtimestr.com\/?p=129587"},"modified":"2020-09-28T14:20:05","modified_gmt":"2020-09-28T11:20:05","slug":"covid-19-kitlesel-bagisikliginda-t-hucrelerinin-onemi","status":"publish","type":"post","link":"https:\/\/epochtimestr.com\/index.php\/covid-19-kitlesel-bagisikliginda-t-hucrelerinin-onemi","title":{"rendered":"COVID-19 Kitlesel Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131nda T H\u00fccrelerinin \u00d6nemi"},"content":{"rendered":"\n
\"\"
Florida\u2019da otoyoldaki korona test merkezinde yolculara koronavir\u00fcs (COVID-19) testi yap\u0131l\u0131yor (NTD haberi)<\/figcaption><\/figure><\/div>\n\n\n\n

Son zamanlarda COVID-19 kitlesel ba\u011f\u0131\u015f\u0131kl\u0131k<\/a> hakk\u0131ndaki tart\u0131\u015fmalar h\u0131z kazand\u0131. \u00c7\u00fcnk\u00fc yeni ara\u015ft\u0131rmalara g\u00f6re, insanlar\u0131n ba\u011f\u0131\u015f\u0131kl\u0131k sistemi vir\u00fcs\u00fc tan\u0131ma yetene\u011fine sahip ve bu y\u00fczden baz\u0131 ki\u015filerde sadece hafif belirtiler g\u00f6r\u00fcl\u00fcyor veya hi\u00e7bir belirti g\u00f6r\u00fclm\u00fcyor.<\/p>\n\n\n\n

Kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131, \u00e7ok say\u0131da insanda bir hastal\u0131\u011fa kar\u015f\u0131 – ge\u00e7irdi\u011fi enfeksiyondan ya da a\u015f\u0131lamadan dolay\u0131 – ba\u011f\u0131\u015f\u0131k geli\u015fti\u011finde olu\u015fur; bu durum, yay\u0131lmay\u0131 durdurur veya yava\u015flat\u0131r. B\u00f6ylece hastal\u0131\u011f\u0131 ge\u00e7irmemi\u015f olanlar da dahil olmak \u00fczere t\u00fcm toplumu korur.<\/p>\n\n\n\n

Kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n\u0131 sa\u011flamak i\u00e7in gerekli y\u00fczdeler hakk\u0131nda tahmin y\u00fcr\u00fct\u00fcl\u00fcrken, esas olarak COVID-19<\/a>\u2019dan kurtulmu\u015f olanlardan al\u0131nan antikorlar \u00fczerine odaklan\u0131lm\u0131\u015ft\u0131r. Ancak bilim adamlar\u0131 antikorlar\u0131n insanlar\u0131, enfeksiyonun tekrarlamas\u0131na kar\u015f\u0131 ne kadar s\u00fcre korudu\u011fundan hala emin de\u011filler.<\/p>\n\n\n\n

Son zamanlarda yap\u0131lan ara\u015ft\u0131rmalarda art\u0131k, T h\u00fccrelerinin COVID-19 i\u00e7in kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131na katk\u0131s\u0131 da dikkate al\u0131n\u0131yor.<\/p>\n\n\n\n

COVID-19 i\u00e7in T H\u00fccresi Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131<\/strong><\/h3>\n\n\n\n
\"\"
Foto\u011fraf: Pexels<\/figcaption><\/figure><\/div>\n\n\n\n

Ulusal Sa\u011fl\u0131k Enstit\u00fcleri Direkt\u00f6r\u00fc Dr. Francis Collins yay\u0131nlad\u0131\u011f\u0131 bir blog g\u00f6nderisi<\/a>nde, COVID-19 hastal\u0131\u011f\u0131na neden olan vir\u00fcs olan SARS-CoV-2\u2019ye kar\u015f\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k tepkisi \u00fczerine yap\u0131lan \u00e7al\u0131\u015fmalar\u0131n, hastal\u0131\u011fa kar\u015f\u0131 ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131m\u0131z olup olmayaca\u011f\u0131n\u0131 belirlemek i\u00e7in \u00e7o\u011funlukla v\u00fccudun antikor \u00fcretimine odakland\u0131\u011f\u0131n\u0131 s\u00f6yledi.<\/p>\n\n\n\n

Collins, \u201cAma asl\u0131nda, haf\u0131za T h\u00fccreleri olarak bilinen ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri, ba\u011f\u0131\u015f\u0131kl\u0131k sistemimizin bizi bir\u00e7ok viral enfeksiyona kar\u015f\u0131 koruma kabiliyetinde \u00f6nemli bir rol oynamaktad\u0131r; g\u00f6r\u00fcn\u00fc\u015fe bak\u0131l\u0131rsa bunlara COVID-19 da d\u00e2hildir\u201d dedi.<\/p>\n\n\n\n

T h\u00fccreleri (B h\u00fccreleriyle birlikte), antijenleri – v\u00fccudu istila eden yabanc\u0131 maddeleri – yok etme ve hat\u0131rlama konusunda v\u00fccuda yard\u0131mc\u0131 olarak adaptif ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde \u00f6nemli bir rol oynayan bir t\u00fcr beyaz kan h\u00fccresidir. T h\u00fccreleri kemik ili\u011finde \u00fcretilse de, g\u00f6\u011f\u00fcs kemi\u011finin hemen arkas\u0131nda, akci\u011ferler aras\u0131nda k\u00fc\u00e7\u00fck bir organ olan tim\u00fcse giderler ve burada olgunla\u015farak belirli rollere sahip farkl\u0131 T h\u00fccrelerine d\u00f6n\u00fc\u015f\u00fcrler.<\/p>\n\n\n\n

\u0130nsanlar ya\u015fland\u0131k\u00e7a tim\u00fcste meydana gelen k\u00fc\u00e7\u00fclme, T h\u00fccrelerinin \u00fcretimini ve i\u015flevselli\u011fini etkiler. Bu nedenle 60 ya\u015f ve \u00fcst\u00fc yeti\u015fkinler enfeksiyonlara kar\u015f\u0131 daha duyarl\u0131 hale gelir. Ya\u015fl\u0131 n\u00fcfus, salg\u0131ndan en \u00e7ok etkilenen grup olmu\u015ftur. \u00c7ift ihtisasl\u0131 t\u0131p ve cerrahi uzman\u0131 Dr. Tom Reed, Teksas eyaleti Senat\u00f6r\u00fc Bob Hall taraf\u0131ndan d\u00fczenlenen bir Facebook tart\u0131\u015fmas\u0131<\/a>nda, \u201ct\u00fcm COVID \u00f6l\u00fcmlerinin en az y\u00fczde 45\u2019ini n\u00fcfusun y\u00fczde 0,62\u2019si olan – huzurevlerinde ve destekli ya\u015fam tesislerinde ya\u015fayanlar\u0131n olu\u015fturdu\u011funu\u201d anlatt\u0131.<\/p>\n\n\n\n

Collins\u2019in de kendi blogunda at\u0131fta bulundu\u011fu, Nature\u2019da yay\u0131nlanan bir \u00e7al\u0131\u015fma<\/a>, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi T h\u00fccrelerinin \u201cinsanlarda bulunan di\u011fer koronavir\u00fcslerle ge\u00e7mi\u015f kar\u015f\u0131la\u015fmalar\u0131 hat\u0131rlayarak\u201d COVID-19\u2019a kar\u015f\u0131 koruma sa\u011flayabilece\u011fini \u00f6ne s\u00fcr\u00fcyor ve baz\u0131 ki\u015filerin neden bu hastal\u0131kla sava\u015fabildi\u011fini veya yaln\u0131zca hafif belirtilerle atlatabildi\u011fini bu \u015fekilde a\u00e7\u0131kl\u0131yor.<\/p>\n\n\n\n

\u0130nsanlara bula\u015fan SARS-CoV-2\u2019den ba\u015fka alt\u0131 koronavir\u00fcs daha var: d\u00f6rd\u00fc so\u011fuk alg\u0131nl\u0131\u011f\u0131na neden olurken, ikisi 2003\u2019te \u015eiddetli Akut Solunum Sendromu (SARS) salg\u0131n\u0131na ve 2012\u2019de Orta Do\u011fu Solunum Sendromu (MERS) salg\u0131n\u0131na neden oldu. Bu koronavir\u00fcsler, enfekte ki\u015filerde hem haf\u0131za T h\u00fccreleri hem de antikorlar \u00fcretti. Ancak ara\u015ft\u0131rmaya g\u00f6re, on y\u0131ldan fazla bir s\u00fcredir ba\u011f\u0131\u015f\u0131kl\u0131k kazand\u0131rmaya devam eden, haf\u0131za T h\u00fccreleriydi.<\/p>\n\n\n\n

Nature\u2019de yay\u0131nlanan ara\u015ft\u0131rmadan sonra, benzer sonu\u00e7lar\u0131 do\u011frulayan \u00e7ok say\u0131da \u00e7al\u0131\u015fma yay\u0131nland\u0131.<\/p>\n\n\n\n

Cell\u2019de yak\u0131n zamanda yay\u0131nlanan \u00e7al\u0131\u015fma (pdf<\/a>), T h\u00fccrelerinin COVID-19\u2019a kar\u015f\u0131 kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131n\u0131n geli\u015ftirilmesinde daha umut verici bir rol oynad\u0131\u011f\u0131n\u0131 g\u00f6stermektedir.<\/p>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar, \u201cBa\u011f\u0131\u015f\u00e7\u0131lardan al\u0131nan haf\u0131za T-h\u00fccrelerinin, SARS-CoV-2\u2019ye \u00f6zg\u00fc antikorlara sahip olmayan ki\u015filerde bile, enfeksiyondan aylar sonra g\u00fc\u00e7l\u00fc tepkiler sergiledi\u011fini; bunun da COVID-19\u2019a kar\u015f\u0131 daha \u00f6nceden geli\u015ftirilmi\u015f, beklenmeyen d\u00fczeyde bir kitlesel ba\u011f\u0131\u015f\u0131kl\u0131\u011fa i\u015faret etti\u011fini\u201d buldu.<\/p>\n\n\n\n

Ba\u015fkan Donald Trump\u2019\u0131n salg\u0131nla ilgili yeni dan\u0131\u015fman\u0131 Dr. Scott Atlas, ge\u00e7en aylarda ortaya \u00e7\u0131kan verilerin, enfekte olmayan ki\u015filerin de COVID-19 ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131na sahip oldu\u011funu g\u00f6sterdi\u011fini s\u00f6yledi<\/a>. \u201cBu muhtemelen, zaten mevcut olan ve \u015fimdi de y\u0131llarca s\u00fcrd\u00fc\u011f\u00fc ispat edilen, T-h\u00fccresi ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131ndan kaynaklan\u0131yor\u201d dedi.<\/p>\n\n\n\n

Atlas Fox News\u2019e yapt\u0131\u011f\u0131 konu\u015fmada, Singapur\u2019da ve \u0130sve\u00e7\u2019in Karolinska Enstit\u00fcs\u00fc\u2019nde yap\u0131lan ara\u015ft\u0131rmalara dikkat \u00e7ekti. Enstit\u00fcdeki ara\u015ft\u0131rmac\u0131lar<\/a>, hafif veya belirti g\u00f6stermeyen COVID-19 vakalar\u0131 ge\u00e7iren bir\u00e7ok ki\u015finin, SARS-CoV-2\u2019ye T h\u00fccrelerine dayal\u0131 ba\u011f\u0131\u015f\u0131kl\u0131k g\u00f6sterdi\u011fini a\u00e7\u0131klad\u0131.<\/p>\n\n\n\n

Kitle Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131na Ula\u015fmak<\/strong><\/p>\n\n\n\n

\"\"
Foto\u011fraf: Pixabay<\/figcaption><\/figure><\/div>\n\n\n\n

Genel olarak, kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131na ula\u015f\u0131lmadan \u00f6nce n\u00fcfusun tahminen y\u00fczde 60 ila 70\u2019inin SARS-CoV-2 ile enfekte olmas\u0131 gerekti\u011fi d\u00fc\u015f\u00fcn\u00fclmektedir. Devine Concierge Medicine<\/a>\u2019in kurucu orta\u011f\u0131, \u00e7ift ihtisasl\u0131 dahiliyeci ve geriatrist Dr. Michael Devine, The Epoch Times\u2019a g\u00f6nderdi\u011fi bir e-postada \u201cBununla birlikte son zamanlarda yap\u0131lan birka\u00e7 \u00e7al\u0131\u015fmada, belirli n\u00fcfus fakt\u00f6rlerine (n\u00fcfus yo\u011funlu\u011fu, seyahat e\u011filimi, hassasl\u0131k vb.) ba\u011fl\u0131 olarak, \u00fclke \u00e7ap\u0131nda baz\u0131 az n\u00fcfuslu yerlerde, bu say\u0131n\u0131n \u00f6nemli \u00f6l\u00e7\u00fcde d\u00fc\u015f\u00fck olabilece\u011fi \u00f6ne s\u00fcr\u00fclmektedir\u201d diye yazd\u0131.<\/p>\n\n\n\n

Ancak baz\u0131 eyaletlerde halihaz\u0131rda kitle ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 g\u00f6r\u00fcl\u00fcp g\u00f6r\u00fclmedi\u011fi soruldu\u011funda Devine, bunun hen\u00fcz tam olarak ger\u00e7ekle\u015fti\u011fine inanmad\u0131\u011f\u0131n\u0131 s\u00f6yl\u00fcyor.<\/p>\n\n\n\n

Devine \u201c\u015eu anda sahip oldu\u011fumuz her \u00f6l\u00e7ekte, do\u011frudan (enfekte olarak) veya do\u011fu\u015ftan kazan\u0131lm\u0131\u015f (do\u011fal olarak var olan veya genetik olarak uyarlanm\u0131\u015f) ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 olan n\u00fcfus oran\u0131, kitlesel ba\u011f\u0131\u015f\u0131kl\u0131k sonucunu \u00e7\u0131karacak herhangi bir tahmin modeli i\u00e7in, b\u00fcy\u00fck \u00f6l\u00e7\u00fcde yetersiz kal\u0131yor\u201d diyor.<\/p>\n\n\n\n

\u201c\u015eu anda baz\u0131 eyaletlerde g\u00f6r\u00fclen vakalardaki sevindirici azalma, toplumdaki – sosyal mesafe, toplum i\u00e7inde y\u00fcz maskelerinin kullan\u0131lmas\u0131 ve el hijyeninin s\u00fcrd\u00fcr\u00fclmesi gibi – sa\u011fl\u0131k al\u0131\u015fkanl\u0131klar\u0131n\u0131n sonucudur\u201d<\/p>\n\n\n\n

Devine ayr\u0131ca, seyahatlerin s\u0131n\u0131rland\u0131r\u0131lmas\u0131, havan\u0131n \u0131s\u0131nmas\u0131 ve insanlar\u0131n \u201ckapal\u0131 mekanda mahsur kalmak yerine d\u0131\u015far\u0131da daha fazla vakit ge\u00e7irmesinin\u201d vir\u00fcs\u00fcn yay\u0131lmas\u0131nda azalmaya katk\u0131da bulunabilece\u011fini s\u00f6yledi.<\/p>\n\n\n\n

Ulusal Alerji ve Bula\u015f\u0131c\u0131 Hastal\u0131klar Enstit\u00fcs\u00fc m\u00fcd\u00fcr\u00fc Dr. Anthony Fauci, 13 A\u011fustos\u2019ta canl\u0131 bir Instagram oturumunda g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131n\u0131n vir\u00fcs\u00fc \u00f6ld\u00fcrd\u00fc\u011f\u00fcn\u00fc s\u00f6yledi. \u201cOnunla kar\u015f\u0131la\u015ft\u0131\u011f\u0131m\u0131zda, d\u0131\u015far\u0131da, g\u00fcne\u015fte olman\u0131n, i\u00e7eride olmaktan \u00e7ok daha iyi olmas\u0131n\u0131n nedenlerinden biri budur.\u201d<\/p>\n\n\n\n

\u0130nsanlara d\u0131\u015far\u0131da olmalar\u0131n\u0131n tavsiye edilmesinin bir di\u011fer \u00f6nemli nedeni de \u015fudur: cildinizi g\u00fcne\u015fte yanmadan, 15-30 dakika boyunca direk g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131na maruz b\u0131rakmak, enfeksiyonlarla sava\u015fmaya ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemini d\u00fczenlemeye yard\u0131mc\u0131 olan \u00f6nemli bir hormon olan D vitamini \u00fcretimini harekete ge\u00e7irmektedir. Ara\u015ft\u0131rmalar, D vitamini eksikli\u011fi<\/a> ile COVID-19 enfeksiyon riski art\u0131\u015f\u0131 aras\u0131nda ba\u011flant\u0131 oldu\u011funu bulmu\u015ftur.<\/p>\n\n\n\n

2016 y\u0131l\u0131nda Georgetown \u00dcniversitesi T\u0131p Merkezi taraf\u0131ndan yap\u0131lan bir ara\u015ft\u0131rma<\/a>da, g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131n\u0131n, \u00f6zellikle d\u00fc\u015f\u00fck seviyeli mavi \u0131\u015f\u0131\u011f\u0131n, \u201cinsan ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde \u00f6nemli bir rol oynayan T h\u00fccrelerine enerji vererek\u201d daha h\u0131zl\u0131 hareket etmelerini sa\u011flad\u0131\u011f\u0131n\u0131 bulundu.<\/p>\n\n\n\n

\u00c7al\u0131\u015fman\u0131n ba\u015f ara\u015ft\u0131rmac\u0131s\u0131 Dr. Gerard Ahern bir bas\u0131n b\u00fclteni<\/a>nde, \u201c\u0130ster destekleyici ister \u00f6ld\u00fcr\u00fcc\u00fc olsun T h\u00fccrelerinin, i\u015flerini yapmak yani enfeksiyonun oldu\u011fu b\u00f6lgeye ula\u015fmak ve bir tepki d\u00fczenlemek i\u00e7in harekete ge\u00e7meleri gerekiyor\u201d dedi. \u201cBu \u00e7al\u0131\u015fma g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131n\u0131n, \u00f6nemli ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini hareketlendirerek do\u011frudan aktif hale getirdi\u011fini g\u00f6steriyor\u201d dedi.<\/p>\n\n\n\n

Olas\u0131 Kitlesel Ba\u011f\u0131\u015f\u0131kl\u0131k Alanlar\u0131<\/strong><\/h3>\n\n\n\n

Geni\u015f insan kitlelerinin sosyal mesafeye dikkat etmeden ve baz\u0131lar\u0131 maske takmadan s\u0131k s\u0131k protesto ve tepki g\u00f6sterisi yapt\u0131\u011f\u0131 – Oregon, Washington ve Illinois gibi – eyaletlerde, yeni vakalarda veya \u00f6l\u00fcmlerde \u00f6nemli bir art\u0131\u015f g\u00f6r\u00fclm\u00fcyor.<\/p>\n\n\n\n

Washington Sa\u011fl\u0131k Bakanl\u0131\u011f\u0131, 14 A\u011fustos\u2019ta yay\u0131nlad\u0131\u011f\u0131 tweette, ayaklanmalar\u0131n devam etti\u011fi King County\u2019de bile \u201cCOVID-19 vakalar\u0131nda art\u0131\u015f ya da azalma g\u00f6r\u00fclmedi\u011fini\u201d bildirdi.<\/p>\n\n\n\n

\n

New report highlights COVID-19 cases are plateauing:
\ud83d\udd39 Reproductive # is hovering around one.
\ud83d\udd39 Seeing impacts of people using face coverings across the state.
\ud83d\udd39 Case counts are plateauing or declining in King and Yakima counties. https:\/\/t.co\/qBTL6ePaWs<\/a><\/p>— WA Dept. of Health (@WADeptHealth) August 14, 2020<\/a><\/blockquote>