{"id":169413,"date":"2026-07-29T22:36:15","date_gmt":"2026-07-29T19:36:15","guid":{"rendered":"https:\/\/epochtimestr.com\/?p=169413"},"modified":"2026-07-29T22:36:18","modified_gmt":"2026-07-29T19:36:18","slug":"mali-zorluklar-beyin-yaslanmasini-hizlandiriyor","status":"publish","type":"post","link":"https:\/\/epochtimestr.com\/index.php\/mali-zorluklar-beyin-yaslanmasini-hizlandiriyor","title":{"rendered":"Mali Zorluklar Beyin Ya\u015flanmas\u0131n\u0131 H\u0131zland\u0131r\u0131yor"},"content":{"rendered":"
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Bir ara\u015ft\u0131rma sonucuna g\u00f6re mali zorluklar beyin ya\u015flanmas\u0131n\u0131 h\u0131zland\u0131r\u0131yor. (G\u00f6rsel: Grae Dickason, Pixabay)<\/figcaption><\/figure><\/div>\n\n\n

Mali zorluklar ve de\u011fi\u015ftirilebilir \u00e7evresel etkenlerin bili\u015fsel ya\u015flanmayla nas\u0131l ili\u015fkili olabilece\u011fini daha iyi anlamaya ihtiya\u00e7 var.<\/h2>\n\n\n\n

70 y\u0131l\u0131 a\u015fk\u0131n bir s\u00fcreyi kapsayan b\u00fcy\u00fck bir \u0130ngiliz ara\u015ft\u0131rmas\u0131, \u00e7al\u0131\u015fma hayatlar\u0131 boyunca kronik para<\/a> s\u0131k\u0131nt\u0131s\u0131 ya\u015fayan ki\u015filerin 50’li ya\u015flar\u0131na geldiklerinde haf\u0131za ve i\u015flem h\u0131z\u0131nda \u00f6l\u00e7\u00fclebilir d\u00fc\u015f\u00fc\u015fler g\u00f6sterdi\u011fini ve on y\u0131llar sonra h\u0131zlanm\u0131\u015f beyin<\/a> k\u00fc\u00e7\u00fclmesi belirtileri sergiledi\u011fini ortaya koydu. Bu ili\u015fkiler, erkeklerde, dezavantajl\u0131 bir \u00e7ocukluk ge\u00e7irenlerde, daha yoksul ailelerde b\u00fcy\u00fcyenler ve Alzheimer hastal\u0131\u011f\u0131 riskinin artmas\u0131yla ba\u011flant\u0131l\u0131 olan APOE-\u03b54 genetik varyant\u0131n\u0131 ta\u015f\u0131yanlarda en g\u00fc\u00e7l\u00fc \u015fekilde g\u00f6zlemlendi.<\/p>\n\n\n\n

University College London’dan Dr. Jacques Wels ve meslekta\u015flar\u0131, “Demans, k\u00fcresel hastal\u0131k y\u00fck\u00fcne en b\u00fcy\u00fck katk\u0131da bulunan fakt\u00f6rlerden biridir ve oranlar\u0131n\u0131n \u00f6n\u00fcm\u00fczdeki otuz y\u0131lda \u00fc\u00e7 kat\u0131na \u00e7\u0131karak 150 milyona ula\u015faca\u011f\u0131 tahmin ediliyor” dedi.<\/p>\n\n\n

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(Foto\u011fraf: Pixabay-Loaivat)<\/figcaption><\/figure><\/div>\n\n\n

\u201c\u00c7ocukluk ve yeti\u015fkinlik d\u00f6nemindeki sosyoekonomik ko\u015fullar ile bili\u015fsel i\u015flevler aras\u0131ndaki ili\u015fki, ya\u015fam d\u00f6ng\u00fcs\u00fcn\u00fcn farkl\u0131 a\u015famalar\u0131nda g\u00f6sterilmi\u015ftir\u201d<\/h3>\n\n\n\n

Innovation in Aging dergisinde yay\u0131nlanan \u00e7al\u0131\u015fma<\/a>, MRC Ulusal Sa\u011fl\u0131k ve Geli\u015fim Ara\u015ft\u0131rmas\u0131 (1946 Britanya kohort \u00e7al\u0131\u015fmas\u0131 olarak da bilinir) kapsam\u0131nda ya\u015famlar\u0131 boyunca anket dolduran Birle\u015fik Krall\u0131k’taki 2.759 ki\u015fiden elde edilen verileri inceledi.<\/p>\n\n\n\n

University College London’daki ara\u015ft\u0131rmac\u0131lar, MRC Ulusal Sa\u011fl\u0131k ve Geli\u015fim Ara\u015ft\u0131rmas\u0131’na kat\u0131lan ve 1946 do\u011fumlu 2.759 \u0130ngiliz kat\u0131l\u0131mc\u0131y\u0131 inceledi. Ara\u015ft\u0131rmac\u0131lar, 26 ila 53 ya\u015flar\u0131 aras\u0131nda yakla\u015f\u0131k 2.759 kat\u0131l\u0131mc\u0131n\u0131n hane halk\u0131 gelirini ve faturalar\u0131 \u00f6demede zorluk gibi kendi bildirdikleri mali s\u0131k\u0131nt\u0131lar\u0131 takip ettiler.<\/p>\n\n\n\n

Ara\u015ft\u0131rma ekibi, gen\u00e7 ve orta yeti\u015fkinlik d\u00f6nemlerinde s\u00fcrekli maddi s\u0131k\u0131nt\u0131 \u00e7eken veya s\u00fcrekli d\u00fc\u015f\u00fck gelir elde eden ki\u015filerin 53 ya\u015f\u0131na geldiklerinde bili\u015fsel testlerde daha d\u00fc\u015f\u00fck performans g\u00f6sterdiklerini tespit etti.<\/p>\n\n\n

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(Foto\u011fraf: Pixabay-ArtTower)<\/figcaption><\/figure><\/div>\n\n\n

Ekip, beyin taramas\u0131 yap\u0131lan bir alt gruba bakt\u0131\u011f\u0131nda, s\u00fcrekli mali zorluklar ya\u015fayanlar\u0131n, ya\u015famlar\u0131n\u0131n ilerleyen d\u00f6nemlerinde (69 ila 71 ya\u015flar\u0131 aras\u0131nda) daha k\u00f6t\u00fc beyin sa\u011fl\u0131\u011f\u0131na (daha fazla beyin k\u00fc\u00e7\u00fclmesi de dahil olmak \u00fczere) sahip olduklar\u0131n\u0131 buldu.<\/p>\n\n\n\n

UCL’deki Ya\u015fam Boyu Sa\u011fl\u0131k ve Ya\u015flanma Birimi’nden \u00e7al\u0131\u015fman\u0131n yazar\u0131 Dr. Jacques Wels, Fox News Digital’e verdi\u011fi deme\u00e7te, “[Bili\u015fsel gerilemenin] hem genetik risklerle hem de olumsuz \u00e7ocukluk deneyimleriyle ili\u015fkili oldu\u011funu iyi biliyor olsak da, ya\u015fam boyu s\u00fcren s\u00fcrekli finansal stres deneyimi de dahil olmak \u00fczere, ya\u015fam seyri boyunca neler oldu\u011fu hakk\u0131nda \u00e7ok az \u015fey biliyorduk” dedi. Bir di\u011fer fakt\u00f6r ise, s\u00fcrekli maddi zorluk veya d\u00fc\u015f\u00fck gelir ya\u015fad\u0131\u011f\u0131n\u0131 bildiren yeti\u015fkinler, s\u00f6zel haf\u0131za ve i\u015flem h\u0131z\u0131n\u0131 de\u011ferlendiren bili\u015fsel testlerde daha k\u00f6t\u00fc performans g\u00f6sterdi.<\/p>\n\n\n\n

S\u00fcrekli d\u00fc\u015f\u00fck gelire sahip olanlar\u0131n, beyin k\u00fc\u00e7\u00fclmesi ve ventrik\u00fcllerin geni\u015flemesi gibi ya\u015flanma belirtilerini \u00f6l\u00e7en MR taramalar\u0131na g\u00f6re beyin sa\u011fl\u0131klar\u0131n\u0131n da daha k\u00f6t\u00fc oldu\u011fu g\u00f6r\u00fcld\u00fc. Mali s\u0131k\u0131nt\u0131lar – genellikle temel ev ihtiya\u00e7lar\u0131n\u0131 kar\u015f\u0131layacak para veya kaynak eksikli\u011fi olarak tan\u0131mlan\u0131r – bili\u015fsel bozukluk ve gerileme ile de ili\u015fkilidir. Ekibe g\u00f6re, beyin taramalar\u0131 bulgulara fiziksel bir boyut katt\u0131. Hane halk\u0131 geliri s\u00fcrekli d\u00fc\u015f\u00fck olan kat\u0131l\u0131mc\u0131larda, 70’li ya\u015flar\u0131n\u0131n ba\u015flar\u0131nda, genellikle beyin dokusu kayb\u0131yla ili\u015fkilendirilen bir g\u00f6sterge olan daha b\u00fcy\u00fck ventrik\u00fcl hacmi g\u00f6zlemlendi.<\/p>\n\n\n

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(Foto\u011fraf: Pixabay-ArtTower)<\/figcaption><\/figure><\/div>\n\n\n

Erkeklerde kad\u0131nlara k\u0131yasla beyin hacminde daha h\u0131zl\u0131 k\u00fc\u00e7\u00fclme g\u00f6r\u00fcld\u00fc<\/h3>\n\n\n\n

Ara\u015ft\u0131rmac\u0131lar, yakla\u015f\u0131k iki y\u0131ll\u0131k bir takip s\u00fcresi boyunca beyin hacminin nas\u0131l de\u011fi\u015fti\u011fini incelediklerinde, maddi zorluklar\u0131n geni\u015f kapsaml\u0131 ve do\u011frudan bir etkisine rastlamad\u0131lar.<\/p>\n\n\n\n

Ancak baz\u0131 gruplar \u00f6zellikle etkilenmi\u015f olarak \u00f6ne \u00e7\u0131kt\u0131: S\u00fcrekli mali zorluk ya\u015fayan erkeklerde, kad\u0131nlara k\u0131yasla beyin hacminde genel olarak daha h\u0131zl\u0131 bir k\u00fc\u00e7\u00fclme ve beyindeki s\u0131v\u0131 dolu bo\u015fluklar\u0131n daha h\u0131zl\u0131 b\u00fcy\u00fcmesi g\u00f6r\u00fcld\u00fc. D\u00fc\u015f\u00fck gelirli ailelerde b\u00fcy\u00fcyen ki\u015filer, yeti\u015fkinlikte de mali s\u0131k\u0131nt\u0131 ya\u015fad\u0131klar\u0131nda, haf\u0131zayla ba\u011flant\u0131l\u0131 bir beyin b\u00f6lgesi olan hipokampus atrofisine kar\u015f\u0131 daha savunmas\u0131zd\u0131. Alzheimer hastal\u0131\u011f\u0131 i\u00e7in bilinen en g\u00fc\u00e7l\u00fc genetik risk fakt\u00f6r\u00fc olan APOE-\u03b54 gen varyant\u0131n\u0131 ta\u015f\u0131yanlar, kronik mali s\u0131k\u0131nt\u0131 ya\u015fad\u0131klar\u0131nda en dik beyin hacmi kay\u0131plar\u0131n\u0131 ve Alzheimer patolojisinin bir \u00f6zelli\u011fi olan amiloid protein birikiminin en y\u00fcksek seviyelerini g\u00f6sterdi.<\/p>\n\n\n\n

University College London’dan Profes\u00f6r Praveetha Patalay, “Bulgular\u0131m\u0131z, mali zorluklarla kar\u015f\u0131 kar\u015f\u0131ya olan insanlar\u0131 desteklemenin ve kronik yoksullu\u011fu azaltman\u0131n gelecekte bili\u015fsel gerilemeyi ve bunama vakalar\u0131n\u0131 \u00f6nlemeye de yard\u0131mc\u0131 olabilece\u011fini g\u00f6steriyor” dedi.<\/p>\n\n\n\n

UCL taraf\u0131ndan y\u00fcr\u00fct\u00fclen 1946 Britanya kohort \u00e7al\u0131\u015fmas\u0131, d\u00fcnyan\u0131n en uzun s\u00fcredir aral\u0131ks\u0131z devam eden do\u011fum kohort \u00e7al\u0131\u015fmas\u0131d\u0131r. Kat\u0131l\u0131mc\u0131lar (do\u011fumda kay\u0131t alt\u0131na al\u0131nanlar), bu y\u0131l\u0131n ba\u015flar\u0131nda 80. ya\u015f g\u00fcnlerini kutlad\u0131lar.<\/p>\n\n\n\n

\u00c7al\u0131\u015fma , 23 Temmuz 2026 tarihinde Innovation in Aging dergisinde yay\u0131mland\u0131.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mali zorluklar ve de\u011fi\u015ftirilebilir \u00e7evresel etkenlerin bili\u015fsel ya\u015flanmayla nas\u0131l ili\u015fkili olabilece\u011fini daha iyi anlamaya ihtiya\u00e7 var. 70 y\u0131l\u0131 a\u015fk\u0131n bir s\u00fcreyi kapsayan b\u00fcy\u00fck bir \u0130ngiliz ara\u015ft\u0131rmas\u0131, \u00e7al\u0131\u015fma hayatlar\u0131 boyunca kronik para s\u0131k\u0131nt\u0131s\u0131 ya\u015fayan ki\u015filerin 50’li ya\u015flar\u0131na geldiklerinde haf\u0131za ve i\u015flem h\u0131z\u0131nda \u00f6l\u00e7\u00fclebilir d\u00fc\u015f\u00fc\u015fler g\u00f6sterdi\u011fini ve on y\u0131llar sonra h\u0131zlanm\u0131\u015f beyin k\u00fc\u00e7\u00fclmesi belirtileri sergiledi\u011fini ortaya koydu. 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