{"id":170094,"date":"2026-08-10T18:29:41","date_gmt":"2026-08-10T15:29:41","guid":{"rendered":"https:\/\/epochtimestr.com\/?p=170094"},"modified":"2026-08-10T18:29:42","modified_gmt":"2026-08-10T15:29:42","slug":"yeni-gelistirilen-biyoteknolojik-sakiz-hpv-seviyesini-dusuruyor","status":"publish","type":"post","link":"https:\/\/epochtimestr.com\/index.php\/yeni-gelistirilen-biyoteknolojik-sakiz-hpv-seviyesini-dusuruyor","title":{"rendered":"Yeni Geli\u015ftirilen Biyoteknolojik Sak\u0131z HPV Seviyesini D\u00fc\u015f\u00fcr\u00fcyor"},"content":{"rendered":"
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\"University
University of Pennsylvania’dan yeni ara\u015ft\u0131rma: Biyoteknolojik Sak\u0131z HPV seviyelerini %93 azalt\u0131yor. (Foto\u011fraf: hans, Pixabay)<\/figcaption><\/figure><\/div>\n\n\n

HPV (Human Papilloma Vir\u00fcs\u00fc), cinsel yolla bula\u015fan ve hem kad\u0131nlar\u0131 hem erkekleri etkileyen en yayg\u0131n vir\u00fcs t\u00fcrlerinden biridir. 100\u2019den fazla tipi bulunur; baz\u0131 t\u00fcrleri genital si\u011fillere yol a\u00e7arken, y\u00fcksek riskli baz\u0131 tipler ise rahim a\u011fz\u0131 (serviks) ba\u015fta olmak \u00fczere \u00e7e\u015fitli kanser t\u00fcrlerine neden olabilir. Bu nedenle bir\u00e7ok insan HPV a\u015f\u0131s\u0131n\u0131<\/a> genellikle sadece rahim a\u011fz\u0131 kanserini \u00f6nlemekle ili\u015fkilendirir. Oysa HPV ile a\u011f\u0131z sa\u011fl\u0131\u011f\u0131 aras\u0131ndaki g\u00fc\u00e7l\u00fc ba\u011f\u0131n anla\u015f\u0131lmas\u0131 \u00fczerine bu geleneksel anlay\u0131\u015f da h\u0131zla de\u011fi\u015ftiriyor.<\/p>\n\n\n\n

Pensilvanya \u00dcniversitesi Di\u015f Hekimli\u011fi Fak\u00fcltesi ara\u015ft\u0131rmac\u0131lar\u0131, biyom\u00fchendislik y\u00f6ntemiyle geli\u015ftirilen bir sak\u0131z\u0131n, ba\u015f ve boyun kanserli hastalar\u0131n t\u00fck\u00fcr\u00fck \u00f6rneklerinde HPV seviyelerini %93, oral \u00e7alkalama numunelerinde ise %80 oran\u0131nda azaltt\u0131\u011f\u0131n\u0131 bildirdi<\/a>.<\/p>\n\n\n\n

Bu ara\u015ft\u0131rma hen\u00fcz klinik \u00f6ncesi (laboratuvar) a\u015famas\u0131ndad\u0131r; yani \u00e7al\u0131\u015fma kapsam\u0131nda hi\u00e7bir hasta tedavi amac\u0131yla bu sak\u0131z\u0131 \u00e7i\u011fnememi\u015ftir. Ara\u015ft\u0131rmac\u0131lar yaln\u0131zca hastalardan ald\u0131klar\u0131 t\u00fck\u00fcr\u00fck \u00f6rneklerini laboratuvarda sak\u0131z \u00f6zleriyle bir araya getirmi\u015f ve mikrop seviyelerindeki de\u011fi\u015fimi \u00f6l\u00e7m\u00fc\u015ft\u00fcr. Dolay\u0131s\u0131yla bu \u00e7al\u0131\u015fma, sak\u0131z \u00e7i\u011fnemenin kanseri \u00f6nleyece\u011fini veya tedavi edece\u011fini kesinlikle iddia etmemektedir.<\/p>\n\n\n\n

Bu bulguyu bu kadar \u00f6nemli k\u0131lan iki b\u00fcy\u00fck neden var. Birincisi; y\u00fcksek riskli HPV’nin neden oldu\u011fu kal\u0131c\u0131 a\u011f\u0131z enfeksiyonlar\u0131, bademcik ve dil k\u00f6k\u00fc gibi b\u00f6lgeleri kapsayan orofarenks (yutak) kanseri riskini ciddi oranda art\u0131r\u0131yor olmas\u0131. \u0130kincisi ise \u015fu anda t\u0131p d\u00fcnyas\u0131nda yerle\u015fik bir a\u011f\u0131z i\u00e7i HPV enfeksiyonunu tamamen ortadan kald\u0131racak net bir tedavinin bulunmuyor olmas\u0131.<\/p>\n\n\n

\n
\"(G\u00f6rsel:
(G\u00f6rsel: Pen Medicine web sitesi)<\/figcaption><\/figure><\/div>\n\n\n

Deney Sonu\u00e7lar\u0131 Ger\u00e7ekte Ne G\u00f6steriyor?<\/h3>\n\n\n\n

Bu sak\u0131z, vir\u00fcslere kar\u015f\u0131 sava\u015fan (antiviral) ‘FRIL’ adl\u0131 bir protein (lektin) i\u00e7eren lablab fasulyesi tozundan \u00fcretiliyor. Dr. Henry Daniell liderli\u011findeki ara\u015ft\u0131rma ekibi, bu \u00f6zel proteinin HPV vir\u00fcs\u00fcn\u00fc yakalama yetene\u011fini test etti. Bu ama\u00e7la, ba\u015f ve boyun kanseri olan hastalar\u0131n yan\u0131 s\u0131ra sa\u011fl\u0131kl\u0131 kat\u0131l\u0131mc\u0131lardan al\u0131nan t\u00fck\u00fcr\u00fck ve a\u011f\u0131z \u00e7alkalama \u00f6rnekleri laboratuvarda incelendi.<\/p>\n\n\n\n

Fasulye \u00f6zl\u00fc bu sak\u0131z, t\u00fck\u00fcr\u00fckteki HPV vir\u00fcs\u00fcn\u00fc yakla\u015f\u0131k %93, a\u011f\u0131z \u00e7alkalama suyunda ise %80 oran\u0131nda azaltt\u0131. Hatta baz\u0131 \u00f6rneklerde sak\u0131z\u0131n, ortamdaki t\u00fcm saptanabilir HPV vir\u00fcslerini birbirine ba\u011flay\u0131p k\u00fcmeleyerek tamamen etkisiz hale getirdi\u011fi g\u00f6r\u00fcld\u00fc.<\/p>\n\n\n\n

Ara\u015ft\u0131rma ekibi daha sonra sak\u0131z\u0131, mikroplarla sava\u015fan (antimikrobiyal) ‘protegrin-1’ adl\u0131 bir proteini de \u00fcretecek \u015fekilde geli\u015ftirdi. \u00c7\u00fcnk\u00fc fasulye \u00f6zl\u00fc sak\u0131z\u0131n bakteriler \u00fczerindeki etkisi tek ba\u015f\u0131na s\u0131n\u0131rl\u0131 kalm\u0131\u015ft\u0131. Bu yeni protein eklendi\u011finde, sak\u0131z\u0131n tek bir dozu, ba\u015f ve boyun kanseriyle do\u011frudan ili\u015fkili iki tehlikeli bakteriyi (Porphyromonas gingivalis ve Fusobacterium nucleatum) neredeyse tamamen yok etti. <\/p>\n\n\n\n

Laboratuvar kay\u0131tlar\u0131nda bakteriyel azalman\u0131n 10 bin ila 1 milyon kat (4-6 log) aras\u0131nda oldu\u011fu bildirildi.
Ara\u015ft\u0131rman\u0131n en dikkat \u00e7ekici y\u00f6nlerinden biri de bu tedavinin, a\u011f\u0131z i\u00e7inde do\u011fal olarak bulunan faydal\u0131 bakterilere hi\u00e7bir zarar vermemi\u015f gibi g\u00f6r\u00fcnmesi. Uzmanlar bu durumu, a\u011f\u0131zdaki faydal\u0131 bakterileri yok ederken hastal\u0131\u011fa yol a\u00e7an Candida albicans mantar\u0131n\u0131 (mayas\u0131n\u0131) art\u0131ran radyoterapi y\u00f6ntemiyle kar\u015f\u0131la\u015ft\u0131r\u0131yor. Bilim d\u00fcnyas\u0131nda heyecan yaratan bu bulgular Scientific Reports dergisinde yay\u0131mland\u0131 ve Penn Today platformunda da geni\u015f yer buldu.<\/p>\n\n\n

\n
\"(Foto\u011fraf:
(Foto\u011fraf: Henry Denniel facebook hesab\u0131)<\/figcaption><\/figure><\/div>\n\n\n

Laboratuvardaki bir \u00f6rnek kab\u0131 ile ger\u00e7ek bir hasta aras\u0131ndaki mesafe olduk\u00e7a b\u00fcy\u00fckt\u00fcr.<\/h4>\n\n\n\n

Bu sak\u0131z\u0131n ticari bir \u00fcr\u00fcn haline gelebilmesi i\u00e7in hen\u00fcz ger\u00e7ekle\u015fmemi\u015f olan birka\u00e7 \u00f6nemli a\u015famadan daha ge\u00e7mesi gerekiyor. V\u00fccuttan al\u0131nan \u00f6rnekler \u00fczerinde elde edilen laboratuvar (ex vivo) sonu\u00e7lar\u0131, ayn\u0131 etkinin canl\u0131 bir a\u011f\u0131zda da aynen ger\u00e7ekle\u015fece\u011fini kan\u0131tlamaz. \u00c7\u00fcnk\u00fc ger\u00e7ek bir a\u011f\u0131zda t\u00fck\u00fcr\u00fck s\u00fcrekli olarak \u00fcretilir ve yutulur; sak\u0131z ise saatlerce de\u011fil, sadece dakikalarca \u00e7i\u011fnenir. Dolay\u0131s\u0131yla, canl\u0131 bir a\u011f\u0131z i\u00e7indeki aktif madde konsantrasyonlar\u0131, kontroll\u00fc laboratuvar ortam\u0131nda kullan\u0131lanlardan \u00e7ok daha farkl\u0131 olabilir.<\/p>\n\n\n\n

Bir \u00f6rnekteki saptanabilir vir\u00fcs miktar\u0131n\u0131 azaltmak, enfeksiyonu tamamen ortadan kald\u0131rmakla ayn\u0131 \u015fey de\u011fildir. Yutakta (orofarenks) bulunan HPV, do\u011frudan epitel h\u00fccrelerinin i\u00e7ine yerle\u015fir. Dolay\u0131s\u0131yla t\u00fck\u00fcr\u00fckle temas eden bir sak\u0131z\u0131n, bu h\u00fccrelerin derinliklerindeki enfekte dokuya etkili bir \u015fekilde ula\u015fmas\u0131 m\u00fcmk\u00fcn g\u00f6r\u00fcnmemektedir.<\/p>\n\n\n\n

Sak\u0131z\u0131n a\u011f\u0131zdaki HPV miktar\u0131n\u0131 azaltmas\u0131 bile do\u011frudan daha az kanser vakas\u0131 g\u00f6r\u00fclece\u011fi anlam\u0131na gelmez. \u00c7\u00fcnk\u00fc yutak (orofaringeal) kanserleri, vir\u00fcs\u00fcn kal\u0131c\u0131 hale gelmesinden y\u0131llar, hatta onlarca y\u0131l sonra geli\u015fir. Dolay\u0131s\u0131yla sak\u0131z\u0131n kanseri ger\u00e7ekten \u00f6nledi\u011fini iddia edebilmek i\u00e7in, hastalar\u0131n \u00e7ok uzun y\u0131llar boyunca klinik olarak takip edilmesi gerekir.<\/p>\n\n\n\n

Sak\u0131z\u0131n insanlar \u00fczerindeki tekrarl\u0131 kullan\u0131m g\u00fcvenli\u011fi hen\u00fcz de\u011ferlendirilmemi\u015ftir. Ayr\u0131ca form\u00fcldeki ‘protegrin-1’, mikroplara ve kansere kar\u015f\u0131 g\u00fc\u00e7l\u00fc etkileri olan (antimikrobiyal ve antikanser) aktif bir proteindir. Bu nedenle, sak\u0131z\u0131n kendisinden ba\u011f\u0131ms\u0131z olarak, bu protein i\u00e7in tamamen ayr\u0131 bir toksisite (zehirlilik) de\u011ferlendirmesi yap\u0131lmas\u0131 gerekecektir.<\/p>\n\n\n\n

Ara\u015ft\u0131rma ekibinin lideri Dr. Daniell, elde edilen sonu\u00e7lar\u0131n bu y\u00f6ntemi mevcut kanser tedavilerinin yan\u0131nda destekleyici bir unsur ya da koruyucu bir yakla\u015f\u0131m olarak klinik deney a\u015famas\u0131na ta\u015f\u0131mak i\u00e7in yeterli oldu\u011funu belirtti. Yani bu a\u00e7\u0131klama sak\u0131z\u0131n \u015fu anki kullan\u0131labilirli\u011fini de\u011fil, bir sonraki stratejik ad\u0131mlar\u0131 ifade ediyor.<\/p>\n\n\n\n

S\u00f6z konusu ara\u015ft\u0131rma; Ulusal Sa\u011fl\u0131k Enstit\u00fcleri (NIH), UCLA David Geffen T\u0131p Fak\u00fcltesi Akademik Senato Hibesi ve Ulusal Kanser Enstit\u00fcs\u00fc Kanser Merkezi destek fonlar\u0131 taraf\u0131ndan finanse edilmi\u015ftir. Bu kurumsal destekler, \u00e7al\u0131\u015fman\u0131n resmi raporlar\u0131nda da a\u00e7\u0131k\u00e7a belirtilmi\u015ftir.<\/p>\n\n\n

\n
\"(G\u00f6rsel:
(G\u00f6rsel: appuser, pixabay)<\/figcaption><\/figure><\/div>\n\n\n

A\u011f\u0131z i\u00e7i HPV Neden Giderek Artan Bir Endi\u015fe Kayna\u011f\u0131?<\/h3>\n\n\n\n

Ba\u015f ve boyun b\u00f6lgesindeki yass\u0131 h\u00fccreli kanserler (skuam\u00f6z h\u00fccreli karsinom), a\u011f\u0131z ve bo\u011faz\u0131 kaplayan dokularda ba\u015flar. Olduk\u00e7a agresif (h\u0131zl\u0131 yay\u0131lan) bir t\u00fcr olabilen bu kanserde, te\u015fhis gecikti\u011finde tedavi ba\u015far\u0131 oran\u0131 genellikle d\u00fc\u015f\u00fckt\u00fcr.<\/p>\n\n\n\n

ABD’de sigaraya ba\u011fl\u0131 ba\u015f ve boyun kanserleri azal\u0131rken, \u00f6zellikle erkekler aras\u0131nda HPV ili\u015fkili yutak (orofarenks) kanseri vakalar\u0131 t\u0131rman\u0131\u015fa ge\u00e7mi\u015f durumda. Sevindirici olan \u015fu ki, HPV pozitif yutak kanserleri sigara kaynakl\u0131 olanlara k\u0131yasla tedaviye daha iyi yan\u0131t veriyor. Ancak; genellikle cerrahi, radyasyon ve bazen kemoterapiyi i\u00e7eren bu a\u011f\u0131r tedavi s\u00fcre\u00e7leri; hastalar\u0131n yutma, konu\u015fma ve t\u00fck\u00fcr\u00fck fonksiyonlar\u0131nda kal\u0131c\u0131 hasarlar b\u0131rakabiliyor.<\/p>\n\n\n\n

Asl\u0131nda a\u011f\u0131z i\u00e7i HPV enfeksiyonlar\u0131n\u0131n b\u00fcy\u00fck bir k\u0131sm\u0131 v\u00fccudun ba\u011f\u0131\u015f\u0131kl\u0131k sistemi sayesinde kendili\u011finden ge\u00e7er. Ancak vir\u00fcs\u00fcn kal\u0131c\u0131 hale geldi\u011fi k\u00fc\u00e7\u00fck bir az\u0131nl\u0131k, kanser riskini do\u011furan as\u0131l tehlikeli a\u015famad\u0131r. \u00dcstelik kad\u0131nlardaki rahim a\u011fz\u0131 taramalar\u0131na benzer, rutin olarak uygulanan bir a\u011f\u0131z i\u00e7i HPV tarama testi bulunmad\u0131\u011f\u0131 gibi; saptanan bir enfeksiyonu tamamen ortadan kald\u0131racak yerle\u015fik bir tedavi y\u00f6ntemi de hen\u00fcz mevcut de\u011fildir.<\/p>\n\n\n\n

Dikkat edilmesi gereken belirtiler aras\u0131nda; ge\u00e7meyen bo\u011faz a\u011fr\u0131s\u0131, boyunda s\u00fcrekli bir \u015fi\u015flik, yutma g\u00fc\u00e7l\u00fc\u011f\u00fc veya a\u011fr\u0131s\u0131, tek tarafl\u0131 ve a\u00e7\u0131klanamayan kulak a\u011fr\u0131s\u0131, birka\u00e7 haftada iyile\u015fmeyen a\u011f\u0131z yaralar\u0131 ya da iki-\u00fc\u00e7 haftadan uzun s\u00fcren ses de\u011fi\u015fiklikleri yer al\u0131r. Bu semptomlara genellikle kanserden \u00e7ok daha basit rahats\u0131zl\u0131klar neden olur; ancak kendi kendine ge\u00e7mesini beklemek yerine mutlaka uzman bir hekim taraf\u0131ndan muayene edilmelidirler.<\/p>\n\n\n

\n
\"\"
Dr.Henry Daniell- Penn Dental Medicine)<\/figcaption><\/figure><\/div>\n\n\n

Var olan korunma y\u00f6ntemleri<\/h3>\n\n\n\n

Bu sak\u0131z\u0131n klinik kullan\u0131ma girmesine daha y\u0131llar olsa da, vir\u00fcse kar\u015f\u0131 halihaz\u0131rda var olan son derece etkili bir korunma y\u00f6ntemi (HPV a\u015f\u0131s\u0131) zaten mevcut; ancak toplumda hen\u00fcz yeterince kullan\u0131lm\u0131yor. HPV a\u015f\u0131s\u0131, yutak (orofarenks) kanseri de dahil olmak \u00fczere bu vir\u00fcsle ili\u015fkili kanserlerin \u00e7o\u011fundan sorumlu olan y\u00fcksek riskli tiplere kar\u015f\u0131 koruma sa\u011flar. Rutin olarak 11-12 ya\u015flar\u0131nda yap\u0131lmas\u0131 \u00f6nerilen a\u015f\u0131ya, asl\u0131nda 9 ya\u015f\u0131ndan itibaren ba\u015flanabilir. Daha \u00f6nce yeterli dozda a\u015f\u0131lanmam\u0131\u015f olanlar i\u00e7in 26 ya\u015f\u0131na kadar telafi a\u015f\u0131lamas\u0131 \u00f6nerilir. 27-45 ya\u015f aras\u0131ndaki yeti\u015fkinler ise kendi risk durumlar\u0131na g\u00f6re a\u015f\u0131lanma konusunu bir hekimle g\u00f6r\u00fc\u015febilirler.<\/p>\n\n\n\n

Sigara kullanmamak ve alkol t\u00fcketimini s\u0131n\u0131rlamak, genel olarak ba\u015f ve boyun kanseri riskini ciddi oranda azalt\u0131r. Bunun yan\u0131 s\u0131ra, d\u00fczenli di\u015f hekimi kontrolleri de hayati \u00f6nem ta\u015f\u0131r; \u00e7\u00fcnk\u00fc di\u015f hekimleri a\u011f\u0131z i\u00e7ini detayl\u0131ca muayene ederek olas\u0131 \u015f\u00fcpheli dokular\u0131 (lezyonlar\u0131) \u00e7ok erken bir evrede te\u015fhis edebilirler.
K\u0131sacas\u0131 bu \u00e7al\u0131\u015fmay\u0131, \u015fu an piyasada bulunan herhangi bir sak\u0131z \u00fcr\u00fcn\u00fcn\u00fc sat\u0131n almak i\u00e7in bir gerek\u00e7e olarak g\u00f6rmemelisiniz. \u00c7\u00fcnk\u00fc piyasadaki hi\u00e7bir \u00fcr\u00fcn, bu testlerde kullan\u0131lan ‘FRIL’ veya ‘protegrin-1’ maddelerini i\u00e7ermemektedir. Dolay\u0131s\u0131yla bu ara\u015ft\u0131rmay\u0131 kaynak g\u00f6stererek pazarlanan herhangi bir \u00fcr\u00fcn, bilimsel ger\u00e7eklerle ba\u011fda\u015fmayan, as\u0131ls\u0131z bir iddiada bulunmu\u015f say\u0131l\u0131r.<\/p>\n\n\n\n

E\u011fer ba\u015f ve boyun kanseri tedavisi g\u00f6rd\u00fcyseniz, a\u011f\u0131z ve di\u015f sa\u011fl\u0131\u011f\u0131n\u0131z\u0131 mutlaka onkoloji ekibinizle planlay\u0131n. Baz\u0131 \u00fcr\u00fcnler mevcut tedavilerinizle etkile\u015fime girebilece\u011finden, doktorunuza dan\u0131\u015fmadan a\u011f\u0131z floras\u0131na (mikrobiyomuna) y\u00f6nelik hi\u00e7bir takviye veya ticari \u00fcr\u00fcn kullanmay\u0131n.<\/p>\n\n\n\n

Ara\u015ft\u0131rma Hakk\u0131nda<\/h3>\n\n\n\n

Henry Daniell, Pennsylvania \u00dcniversitesi Di\u015f Hekimli\u011fi Fak\u00fcltesi Temel ve Translasyonel Bilimler B\u00f6l\u00fcm\u00fc’nde WD Miller Profes\u00f6r\u00fcd\u00fcr.<\/p>\n\n\n\n

\u00c7al\u0131\u015fman\u0131n di\u011fer yazarlar\u0131 aras\u0131nda; Penn Dental Medicine’den Geetanjali Wakade, Rahul Singh ve Smruti Nair; Kansas \u00dcniversitesi T\u0131p Merkezi’nden Andr\u00e9s M. Bur ve Sufi M. Thomas; Los Angeles’taki Kaliforniya \u00dcniversitesi’nden (UCLA) Eri S. Srivatsan ve Marilene B. Wang ile B\u00fcy\u00fck Los Angeles Gaziler \u0130daresi Sa\u011fl\u0131k Sistemi’nden Saroj K. Ba\u015fak yer almaktad\u0131r.<\/p>\n\n\n\n

Bu ara\u015ft\u0131rma; ABD Ulusal Sa\u011fl\u0131k Enstit\u00fcleri (NIH) taraf\u0131ndan Dr. Henry Daniell\u2019e verilen 5-R01-HL 107904-13 numaral\u0131 hibe, UCLA David Geffen T\u0131p Fak\u00fcltesi Akademik Senatosu (Cerrahi E\u011fitim Ara\u015ft\u0131rma program\u0131) Hibesi ve Ulusal Kanser Enstit\u00fcs\u00fc Kanser Merkezi’nin P30 CA168524 numaral\u0131 destek hibesi ile finanse edilmi\u015ftir.<\/p>\n","protected":false},"excerpt":{"rendered":"

HPV (Human Papilloma Vir\u00fcs\u00fc), cinsel yolla bula\u015fan ve hem kad\u0131nlar\u0131 hem erkekleri etkileyen en yayg\u0131n vir\u00fcs t\u00fcrlerinden biridir. 100\u2019den fazla tipi bulunur; baz\u0131 t\u00fcrleri genital si\u011fillere yol a\u00e7arken, y\u00fcksek riskli baz\u0131 tipler ise rahim a\u011fz\u0131 (serviks) ba\u015fta olmak \u00fczere \u00e7e\u015fitli kanser t\u00fcrlerine neden olabilir. Bu nedenle bir\u00e7ok insan HPV a\u015f\u0131s\u0131n\u0131 genellikle sadece rahim a\u011fz\u0131 kanserini […]<\/p>\n","protected":false},"author":13981,"featured_media":170095,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"HPV","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"Bir\u00e7ok insan HPV (\u0130nsan Papilloma Vir\u00fcs\u00fc) a\u015f\u0131s\u0131n\u0131 genellikle sadece rahim a\u011fz\u0131 kanserini \u00f6nlemekle ili\u015fkilendirir.","_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":"","_yoast_wpseo_focuskw_text_input":""},"categories":[519,19],"tags":[12150,12149,12151,12152],"yoast_head":"\nYeni Geli\u015ftirilen Biyoteknolojik Sak\u0131z HPV Seviyesini D\u00fc\u015f\u00fcr\u00fcyor - The Epoch Times TR<\/title>\n<meta name=\"description\" content=\"Bir\u00e7ok insan HPV (\u0130nsan Papilloma Vir\u00fcs\u00fc) a\u015f\u0131s\u0131n\u0131 genellikle sadece rahim a\u011fz\u0131 kanserini \u00f6nlemekle ili\u015fkilendirir.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/epochtimestr.com\/index.php\/yeni-gelistirilen-biyoteknolojik-sakiz-hpv-seviyesini-dusuruyor\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Yeni Geli\u015ftirilen Biyoteknolojik Sak\u0131z HPV Seviyesini D\u00fc\u015f\u00fcr\u00fcyor - 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