{"id":43313,"date":"2011-07-11T22:58:47","date_gmt":"2011-07-11T19:58:47","guid":{"rendered":"http:\/\/www.epochtimestr.com\/?p=43313"},"modified":"2022-12-25T20:07:22","modified_gmt":"2022-12-25T17:07:22","slug":"cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu","status":"publish","type":"post","link":"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu","title":{"rendered":"\u00c7ocuklardaki B\u00f6brek Yetmezli\u011finin Sebebi Olan Yeni Bir Gen Bulundu"},"content":{"rendered":"<p style=\"text-align: justify\">&nbsp;<\/p>\n<figure id=\"attachment_43314\" aria-describedby=\"caption-attachment-43314\" style=\"width: 350px\" class=\"wp-caption aligncenter\"><a class=\"highslide\" rel=\"attachment wp-att-43314\" href=\"http:\/\/www.epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\/fatih-ozaltin\/\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-43314\" src=\"http:\/\/www.epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin.jpg\" alt=\"\" width=\"350\" height=\"160\" srcset=\"https:\/\/epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin.jpg 350w, https:\/\/epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin-150x68.jpg 150w, https:\/\/epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin-300x137.jpg 300w, https:\/\/epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin-292x133.jpg 292w\" sizes=\"(max-width: 350px) 100vw, 350px\" \/><\/a><figcaption id=\"caption-attachment-43314\" class=\"wp-caption-text\">Biyolog Zihni Ekim Ta\u015fk\u0131ran (sol ba\u015fta) ve Biyolog T\u00fclin \u0130b\u015firlio\u011flu , Do\u00e7. Dr. Fatih \u00d6zalt\u0131n ile birlikte.<\/figcaption><\/figure>\n<p style=\"text-align: justify\">T\u00dcB\u0130TAK Sa\u011fl\u0131k Birimleri Ara\u015ft\u0131rma Grubu taraf\u0131ndan desteklenen ve Hacettepe \u00dcniversitesi\u2019nde Do\u00e7. Dr. Fatih \u00d6zalt\u0131n ve ekibinin ger\u00e7ekle\u015ftirdi\u011fi \u00e7al\u0131\u015fmada, \u2018PTPRO\u2019 adl\u0131 genin, akraba evilikleri sonucu ortaya \u00e7\u0131kan ve b\u00f6rek yetmezli\u011fi ile devam eden \u00e7ocukluk \u00e7a\u011f\u0131 <strong>*<\/strong><em>nefrotik sendromuna<\/em> neden oldu\u011fu belirlendi.<\/p>\n<p style=\"text-align: justify\">Yap\u0131lan \u00e7al\u0131\u015fma, hastalarda erken tan\u0131 ve tedavi i\u00e7in, hatta baz\u0131 durumlarda hastal\u0131\u011f\u0131n tamamen \u00f6nlenebilmesi anlam\u0131nda umut \u0131\u015f\u0131\u011f\u0131 ta\u015f\u0131yor.<\/p>\n<p style=\"text-align: justify\">Ger\u00e7ekle\u015ftirilen \u00e7al\u0131\u015fma, bu ay genetik alan\u0131n\u0131n sayg\u0131n dergilerinden biri olan American Journal of Human Genetics (AJHG) dergisinde yay\u0131nland\u0131.<\/p>\n<blockquote>\n<p style=\"text-align: justify\"><strong>*<em>Nefrotik Sendrom: <\/em><\/strong><em>Nefrotik sendrom, \u00e7ocuklarda s\u0131k g\u00f6r\u00fclen, idrarla protein kayb\u0131, v\u00fccutta \u015fi\u015flik ve kanda kolesterol y\u00fcksekli\u011fi yapan bir hastal\u0131kt\u0131r. Hastalar\u0131n b\u00fcy\u00fck bir k\u0131sm\u0131 tedaviye iyi yan\u0131t verirken, %10\u2019luk bir k\u0131sm\u0131 tedaviye diren\u00e7 g\u00f6sterir ve diyaliz ya da b\u00f6brek nakli gerektiren kronik b\u00f6brek yetmezli\u011fine ilerleyebilir. Tedaviye diren\u00e7 g\u00f6steren hastalar\u0131n \u00e7o\u011funda, hastal\u0131\u011f\u0131n alt\u0131nda yatan nedenin bir genetik bozukluk oldu\u011fu bilinirken, bu genlerin \u00e7o\u011fu \u015fu ana kadar saptanamad\u0131. Bulunabilen genler ise hastalar\u0131n ancak %15\u2019lik bir b\u00f6l\u00fcm\u00fcn\u00fc a\u00e7\u0131klayabiliyor.<\/em><\/p>\n<\/blockquote>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; T\u00dcB\u0130TAK Sa\u011fl\u0131k Birimleri Ara\u015ft\u0131rma Grubu taraf\u0131ndan desteklenen ve Hacettepe \u00dcniversitesi\u2019nde Do\u00e7. Dr. Fatih \u00d6zalt\u0131n ve ekibinin ger\u00e7ekle\u015ftirdi\u011fi \u00e7al\u0131\u015fmada, \u2018PTPRO\u2019 adl\u0131 genin, akraba evilikleri sonucu ortaya \u00e7\u0131kan ve b\u00f6rek yetmezli\u011fi ile devam eden \u00e7ocukluk \u00e7a\u011f\u0131 *nefrotik sendromuna neden oldu\u011fu belirlendi. Yap\u0131lan \u00e7al\u0131\u015fma, hastalarda erken tan\u0131 ve tedavi i\u00e7in, hatta baz\u0131 durumlarda hastal\u0131\u011f\u0131n tamamen \u00f6nlenebilmesi anlam\u0131nda [&hellip;]<\/p>\n","protected":false},"author":24,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_yoast_wpseo_focuskw":"","_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"","_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"footnotes":"","_yoast_wpseo_focuskw_text_input":""},"categories":[8173,70,19],"tags":[2322,2323,2324],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.0 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u00c7ocuklardaki B\u00f6brek Yetmezli\u011finin Sebebi Olan Yeni Bir Gen Bulundu - The Epoch Times TR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u00c7ocuklardaki B\u00f6brek Yetmezli\u011finin Sebebi Olan Yeni Bir Gen Bulundu - The Epoch Times TR\" \/>\n<meta property=\"og:description\" content=\"&nbsp; T\u00dcB\u0130TAK Sa\u011fl\u0131k Birimleri Ara\u015ft\u0131rma Grubu taraf\u0131ndan desteklenen ve Hacettepe \u00dcniversitesi\u2019nde Do\u00e7. Dr. Fatih \u00d6zalt\u0131n ve ekibinin ger\u00e7ekle\u015ftirdi\u011fi \u00e7al\u0131\u015fmada, \u2018PTPRO\u2019 adl\u0131 genin, akraba evilikleri sonucu ortaya \u00e7\u0131kan ve b\u00f6rek yetmezli\u011fi ile devam eden \u00e7ocukluk \u00e7a\u011f\u0131 *nefrotik sendromuna neden oldu\u011fu belirlendi. Yap\u0131lan \u00e7al\u0131\u015fma, hastalarda erken tan\u0131 ve tedavi i\u00e7in, hatta baz\u0131 durumlarda hastal\u0131\u011f\u0131n tamamen \u00f6nlenebilmesi anlam\u0131nda [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\" \/>\n<meta property=\"og:site_name\" content=\"The Epoch Times TR\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/theepochtimestr\" \/>\n<meta property=\"article:published_time\" content=\"2011-07-11T19:58:47+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-12-25T17:07:22+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin.jpg\" \/>\n<meta name=\"author\" content=\"Yasemin Erdem\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@TheEpochTimesTR\" \/>\n<meta name=\"twitter:site\" content=\"@TheEpochTimesTR\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"Yasemin Erdem\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu#article\",\"isPartOf\":{\"@id\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\"},\"author\":{\"name\":\"Yasemin Erdem\",\"@id\":\"https:\/\/epochtimestr.com\/#\/schema\/person\/a4191798a6b3dfc5ab6197b62adba3e0\"},\"headline\":\"\u00c7ocuklardaki B\u00f6brek Yetmezli\u011finin Sebebi Olan Yeni Bir Gen Bulundu\",\"datePublished\":\"2011-07-11T19:58:47+00:00\",\"dateModified\":\"2022-12-25T17:07:22+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\"},\"wordCount\":252,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/epochtimestr.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu#primaryimage\"},\"thumbnailUrl\":\"http:\/\/www.epochtimestr.com\/wp-content\/uploads\/2011y\/fatih-ozaltin.jpg\",\"keywords\":[\"bobrek yetmezli\u011fi\",\"nefrotik sendrom\",\"Ptpro\"],\"articleSection\":[\"A\u0130LE ve EG\u0130T\u0130M\",\"Bilimsel Ke\u015fifler\",\"Sa\u011fl\u0131k\"],\"inLanguage\":\"tr\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\",\"url\":\"https:\/\/epochtimestr.com\/index.php\/cocuklardaki-bobrek-yetmezliginin-sebebi-olan-yeni-bir-gen-bulundu\",\"name\":\"\u00c7ocuklardaki B\u00f6brek Yetmezli\u011finin Sebebi Olan Yeni Bir Gen Bulundu - 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